WEEK 06
PROTEIN FOLDING
1. How many molecules of amino acids do you take with a piece of 500 grams of meat? (on average an amino acid is ~100 Daltons)
500g=3e26 dalton, /100 dalton = 3e24
CHOSEN PROTEIN: NORRIN
Norrin is a cysteine-rich growth factor that is required for angiogenesis in the eye, ear, brain, and female reproductive organs.
MRKHVLAASFSMLSLLVIMGDTDSKTDSSFIMDSDPRRCMRHHYVDSISHPLYKCSSKMV
LLARCEGHCSQASRSEPLVSFSTVLKQPFRSSCHCCRPQTSKLKALRLRCSGGMRLTATY
RYILSCHCEECNS
Length:133
PDB id :4MY2
structure solved:Deposited: 2013-09-27
protein family
[Superfamily, evalue = 8.69e-03]cl21545, Glycoprotein hormone beta chain homologues ;This family of cystine-knot hormones includes the beta chains of gonadotropins, thyrotropins, follitropins, choriogonadotropins and more. The members are reproductive hormones that consist of two glycosylated chains (alpha and beta), which form a tightly bound dimer.