WEEK 07

GUT MICROBIOME AND MICROFLUIDIC DEVICE


1. treatments

(i) spores

advantages-easy to transport

disadvantages-who to choose, hard to get, firmicutes



(ii) fecal matter transplant

advantages-effective, has technical support

disadvantages-healthy is relative and hard to define, heavy screening required, very tecnical



(iii) live biotherapeutic (LBP)

advantages-robust

disadvantages-how to acquire bacteria, how to deliver (have to make sure bac. is alive across acid gradient)



(iv) prebiotics

advantages-fertilizer for good bacteria, more like gardening

disadvantages-requires strain collection, needs anaerobic culture and bioprocessors, carbohydrate chemistry





2. future application

vaginal biosensor (ph monitor): engineer lactobacillus to excrete color when vaginal fauna ph is out of range.



LAB



isolated a colony from skin and mouth bacteria





LOW COST LASER TAPE MICROFLUIDIC DEVICE

cutting pdms



assembly



sarah test test



working device